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GLUTHATIONE SYSTEM DURING PHYSICAL LOADS AND ALIMENTARY FACTOR IMPACT ON IT

S. A. KOLESOV, R. S. RAKHMANOV, T.V. BLINOVA, L. A. STRAKHOVA, N. V. CHUMAKOV, YU. G. PISKAREV NIZHNY NOVGOROD RESEARCH INSTITUTE FOR HYGIENE AND OCCUPATIONAL PATHOLOGY, NIZHNY NOVGOROD, RUSSIA
Objective: to evaluate the functioning of gluthatione system (GS) in organism of swimmers during considerable endurance physical loads and to reveal the influence of nutritional factors on these features.
Materials and methods: two groups of swimmers were studied. Sportsmen of the first group consumed «Sport nutrition product» (SNP) based on vegetable raw materials, obtained by cryogenic technology in addition to normal diet. In both groups the blood concentrations of reduced gluthatione (RG), oxidized gluthatione (OG), gluthatione reductase, gluthatione transferase, gluthatione peroxidase in blood were analyzed three times as well as parameters of cardio-vascular system and effectiveness of activity were examined.
Results: low initial RG level was revealed in blood of swimmers. At the same time, RG/OG ratio was 25% lower than optimal in both groups. Towards the end of the study, the ratio significantly (50%) increased in group of sportsmen consumed SNP. The same dynamics was also observed by analyzing indices of effectiveness of activity and pulse rate.
Conclusions: dynamics of examined parameters provided evidence that both intensity of physical load and peculiarities of nutrition status may influence on effectiveness of GS function in swimmers. SNP administration increased the effectiveness of activity, but a maximum effect was postponed and was observed in a month after cancelling of its administration.
Keywords: 
gluthatione system; adaptation; sportsmen; physical loads; sport nutrition product.