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CARDIAС REMODELING IN YOUNG ATHLETES

N. P. ZHIKINA (1), N. А. KOZIOLOVA (2), A. V. BUSHMAKINA (2), O. L. KONNOVA (1) 1 -PERM MEDICAL EXERCISES DISPENSARY, PERM, RUSSIA 2 -PERM STATE MEDICAL UNIVERSITY NAMED AFTER ACADEMICIAN E. A. WAGNER, PERM, RUSSIA

Objective: to identify the characteristics of the left ventricle (LV) remodeling in young competitive athletes in the presence of life-threatening ventricular ectopic activity as a risk factor for sudden death, and to search diagnostic methods for pathological left ventricular hypertrophy in athletes.
Materials and Methods: the main criteria of cardiac remodeling were the presence or absence of a pathological hypertrophy of the LV in athletes, and the most life-threatening factor was the presence of ventricular ectopic activity. Daily monitoring of ECG was conducted with counting the number of clinically significant extrasystoles (> 30 for each hour of the 24-hour study). Left Ventricular Myocardium Mass Index (LVMMI = left ventricular mass / body surface area) was assessed with the echocardiography. The analysis of ROS-curves was performed to identify the cut-off points: 159,1 g/m2 in men and 147,4 g/m2 in women.
Results: LVMMI, Left Ventricular Mass (LVM), the relative thickness of the lateral LV wall in young competitive athletes was significantly higher than in persons who were not involved in sports, regardless of the type of sport. Severe LV hypertrophy and LV remodeling are more common in athletes with no significant differences in types of remodeling, regardless of the sport. The estimated sensitivity of men was 83.3% (95% CI 28,4-99,5), and specificity – 87.55 (95% CI 47,3-99,7) in women sensitivity was 80.0% (95% CI 24,8-99,5), specificity – 100.0% (95% CI 59,0-100,0).
Conclusions: premature ventricular contraction (PVC) in young competitive athletes was detected in the presence of LVH. LVMMI over 159,1 g/m2 in men and more than 147,4 g/m2 in women is a sign of pathological LVH.
Keywords: 
remodeling of the heart; left ventricular hypertrophy; arrhythmia; athletes.