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THE MECHANISMS OF GENERAL ADAPTATION SYNDROME: INFLUENCE OF INCREASED RESPIRATORY RESISTANCE

YU. YU. BYALOVSKIY (1), S. V. BULATETSKIY (2) 1 -RYAZAN STATE MEDICAL UNIVERSITY NAMED AFTER ACADEMICIAN I.P. PAVLOV OF RUSSIAN MINISTRY OF HEALTH, RYAZAN, RUSSIA 2 -RYAZAN BRANCH OF THE KIKOT MOSCOW UNIVERSITY OF THE MINISTRY OF INTERNAL AFFAIRS OF RUSSIA, RYAZAN, RUSSIA

Objective: to detect the response factor of the components of stress-realizing and stress-limiting systems of the body under short periods of resistive respiratory loads in athletes. Materials and methods: the study included 13 men, masters of sports in judo. Additional respiratory resistance (ARR) was performed as 40% or 60% from 100% Pmmax. The exposure time was 3 min. Indicators of the stress-realizing system included lipid hydroperoxide, malondialdehyde (MDA), adrenaline, and noradrenaline. Markers of activity of stress-limiting system were serotonin, cumu-lative index of plasma antioxidant activity, and catalase.
Results: almost all the studied parame-ters (except of noradrenaline under the ARR of 40% from Pmmax and MDA under the ARR of 60% from Pmmax) experienced a significant response factor. The increase of the value of respira-tory resistance was accompanied by increasing of the influence of organized factor of adrenaline and noradrenaline on the components of the stress-realizing system and decreasing of the effect of hydroperoxides and malondialdehyde.
Conclusions: 1. The additional respiratory resistance activates the mechanisms of general adaptation atory resistance can be used in the assessment of the state of adaptation mechanisms.
Keywords: 
additional respiratory resistance; the general adaptation syndrome; stress-realizing and stress-limiting systems.