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NON-STEROIDAL ANTI-INFLAMMATORY DRUGS: CURRENT USE AND NEW PERSPECTIVES

A. S. ZHESTOVSKAYA , V. G. KUKES SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY, MOSCOW, RUSSIA
Non-steroidal anti-inflammatory drugs (NSAIDs) are a medication widely used to treat a range of conditions. Prostaglandins are hormone-like chemicals in the body that contribute to inflammation, pain and fever, by raising temperature and dilating the blood vessels in the place they are released. NSAIDs block a specific enzyme called cyclooxygenase (COX) used by the body to make prostaglandins. By reducing production of prostaglandins, NSAIDs help relieve the discomfort of fever and reduce inflammation and the associated pain. Aceclofenac is a drug for the safe and effective topical delivery.
Keywords: 
non-steroidal anti-inflammatory drugs; cyclooxygenase; aceclofenac; adverse drug reactions; rational drug use.