The Journal is included in Russian and International Library and Abstract Databases:
Russain Science Index (Russia)
Electronic Library (Russia)
DOI Registration Agency (USA)
Ulrich's Periodicals Directory (USA)
Scientific Indexing Services (USA)
InfoBase Index (India)

TRANSCRANIAL LOW-FREQUENCY RHYTHMIC ELECTRO-STIMULATION OF HUMAN SUBCORTEX FOR PREVENTION OF OVEREXCITATION OF THE NERVOUS SYSTEM INDUCED BY INTAKE OF HIGH DOSES OF CAFFEINE IN TRAINING AND AFTER COMPETITION PERIODS

N. N. KARKISCHENKO (1), V. N. KARKISCHENKO (1), D. B. CHAYVANOV (2), YU. A. CHUDINA (2), E. B. SHUSTOV (1), A. A. EMELYANOV (2), A. E. EMELYANOVA (2) 1 -SCIENTIFIC CENTER OF BIOMEDICAL TECHNOLOGIES OF FEDERAL MEDICAL AND BIOLOGICAL AGENCY, SVETLYE GORY, MOSCOW REGION, RUSSIA 2 -NATIONAL RESEARCH CENTRE «KURCHATOV INSTITUTE», MOSCOW, RUSSIA

Objective: to investigate the possibility of using low-frequency rhythmic electrical stimulation of subcortical structures of human brain for correction of hyperactivation of the nervous system^ caused by intake of a large dose of caffeine. Materials and methods: the study was conducted on 24 male athletes (mean age 22.5±2.5 years, mean body mass 64.0±3 kg). «Electroson AGSAR-01» was used for transcranial electrical stimulation of orbital-occipital zone with rectangular pulses with a frequency of 6 Hz. Before the experiment the athletes took 300 mg of caffeine and after performed a 10 km run. Respiratory parameters, heart rate, SpO2 were registered during the run.
Results: transcranial electrical stimulation improved the recovery in athletes and inactivated the effect of caffeine, also in a 25-minutes period improved reaction response and optimized physiological processes which was presented in increased respiratory and cardiac activity.
Conclusions: low-frequency rhythmic electrical stimulation can effectively relieve caffeine hyperactivation of the nervous system in athletes. Detected changes in the indices of respiratory and cardiac activity, accompanying a state of electrically induced state of sleep, are comparable to a state of relaxation.
Keywords: 
caffeine; nervous system hyperactivation; low-frequency transcranial electrical stimulation; electrically induced sleep; frequency; amplitude; respiratory minute volume; heart rate; oxygen saturation of blood.